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simoa planar array (sp-x  (Quanterix)


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    Structured Review

    Quanterix simoa planar array (sp-x
    Comparison of IL-11 reference standard curve performance for (a) “free” human/cyno IL-11 assay on MSD, <t>Simoa</t> HD-1 and <t>SP-X,</t> and (b) “free” mouse IL-11 on MSD and Simoa SP-X, normalized by signal/background.
    Simoa Planar Array (Sp X, supplied by Quanterix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/simoa+planar+array+(sp-x/pmc09348130-103-8-7
    Average 90 stars, based on 1 article reviews
    simoa planar array (sp-x - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic"

    Article Title: Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic

    Journal: mAbs

    doi: 10.1080/19420862.2022.2104153

    Comparison of IL-11 reference standard curve performance for (a) “free” human/cyno IL-11 assay on MSD, Simoa HD-1 and SP-X, and (b) “free” mouse IL-11 on MSD and Simoa SP-X, normalized by signal/background.
    Figure Legend Snippet: Comparison of IL-11 reference standard curve performance for (a) “free” human/cyno IL-11 assay on MSD, Simoa HD-1 and SP-X, and (b) “free” mouse IL-11 on MSD and Simoa SP-X, normalized by signal/background.

    Techniques Used: Comparison

    Related Articles

    Biomarker Discovery:

    Article Title: Analytical Validation and Performance of a Blood-Based P-tau217 Diagnostic Test for Alzheimer Disease.
    Article Snippet: .. The objective of this manuscript is to report the analytical validation of a plasma P-tau217 immunoassay on a Quanterix SP-X (using Simoa® Planar Array technology) platform (13) and its performance using Aβ PET as the comparator method. .. This study used the same capture and detection antibodies as those previously published (5, 7, 8, 11, 14, 15) that assessed Lilly’s P-tau217 assay on the Meso Scale Discovery platform.

    Clinical Proteomics:

    Article Title: Analytical Validation and Performance of a Blood-Based P-tau217 Diagnostic Test for Alzheimer Disease.
    Article Snippet: .. The objective of this manuscript is to report the analytical validation of a plasma P-tau217 immunoassay on a Quanterix SP-X (using Simoa® Planar Array technology) platform (13) and its performance using Aβ PET as the comparator method. .. This study used the same capture and detection antibodies as those previously published (5, 7, 8, 11, 14, 15) that assessed Lilly’s P-tau217 assay on the Meso Scale Discovery platform.

    Positron Emission Tomography:

    Article Title: Analytical Validation and Performance of a Blood-Based P-tau217 Diagnostic Test for Alzheimer Disease.
    Article Snippet: .. The objective of this manuscript is to report the analytical validation of a plasma P-tau217 immunoassay on a Quanterix SP-X (using Simoa® Planar Array technology) platform (13) and its performance using Aβ PET as the comparator method. .. This study used the same capture and detection antibodies as those previously published (5, 7, 8, 11, 14, 15) that assessed Lilly’s P-tau217 assay on the Meso Scale Discovery platform.



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    Figure 6. Comparison of IL-11 reference standard curve performance for (a) “free” human/cyno IL-11 assay on MSD, <t>Simoa</t> HD-1 and SP-X, and (b) “free” mouse IL-11 on MSD and Simoa SP-X, normalized by signal/background.
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    Image Search Results


    Comparison of IL-11 reference standard curve performance for (a) “free” human/cyno IL-11 assay on MSD, Simoa HD-1 and SP-X, and (b) “free” mouse IL-11 on MSD and Simoa SP-X, normalized by signal/background.

    Journal: mAbs

    Article Title: Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic

    doi: 10.1080/19420862.2022.2104153

    Figure Lengend Snippet: Comparison of IL-11 reference standard curve performance for (a) “free” human/cyno IL-11 assay on MSD, Simoa HD-1 and SP-X, and (b) “free” mouse IL-11 on MSD and Simoa SP-X, normalized by signal/background.

    Article Snippet: The final pairs were transferred to the Quanterix Simoa Planar Array (SP-X) platform for further sensitivity improvement.

    Techniques: Comparison

    Levels of plasma cytokine release. Ultrasensitive multiplex measure of human cytokines IL-12, IL-6, IL-1, IL-8, IL-4, IL-22, IL-5, and IL-10, and IFN-γ and TNF-α before (pre) and after (post) vaccination in SAD, CVID and healthy controls.

    Journal: Annals of Allergy, Asthma & Immunology

    Article Title: Antibody and T-cell responses to COVID-19 Vaccination in Common Variable Immunodeficiency and Specific Antibody Deficiency

    doi: 10.1016/j.anai.2023.01.025

    Figure Lengend Snippet: Levels of plasma cytokine release. Ultrasensitive multiplex measure of human cytokines IL-12, IL-6, IL-1, IL-8, IL-4, IL-22, IL-5, and IL-10, and IFN-γ and TNF-α before (pre) and after (post) vaccination in SAD, CVID and healthy controls.

    Article Snippet: Ultrasensitive Quanterix Simoa planar array technology, and the SP-X imaging and analyzed using the Quanterix SP-X Analysis software.

    Techniques: Multiplex Assay

    Figure 6. Comparison of IL-11 reference standard curve performance for (a) “free” human/cyno IL-11 assay on MSD, Simoa HD-1 and SP-X, and (b) “free” mouse IL-11 on MSD and Simoa SP-X, normalized by signal/background.

    Journal: mAbs

    Article Title: Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic.

    doi: 10.1080/19420862.2022.2104153

    Figure Lengend Snippet: Figure 6. Comparison of IL-11 reference standard curve performance for (a) “free” human/cyno IL-11 assay on MSD, Simoa HD-1 and SP-X, and (b) “free” mouse IL-11 on MSD and Simoa SP-X, normalized by signal/background.

    Article Snippet: Custom “homebrew” SP-X (Simoa Planar Array Technology) assays use all reagents as sourced in their Homebrew kit, with Quanterix pre-coated plates with an antibody (high density, circular spotted coating) with high specificity for the Quanterix proprietary peptide.

    Techniques: Comparison